ENFINIA™ IVT Ready DNA Poly(A) Tail Options
What poly(A) tail options are available for IVT Ready DNA
We offer both continuous and segmented poly(A) tails for ENFINIA™ IVT Ready DNA:
- Continuous: A70, A90, A100, A110, A120, A130
- Segmented: A30-Linker-A70, A30-Linker-A90
Segmented poly(A) tails contain a 10 bp UGC linker (5’-GCATATGACT-3’) that separates the two deoxyadenosine homopolymers (see Chaudhary, N. 2021. mRNA vaccines for infectious diseases: principles, delivery and clinical translation)
Note: All poly(A) tails include a 3-T overhang on the sense strand.
For poly(A) tail lengths not listed above, please reach out to your Elegen sales representative.